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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTB
All Species:
40.91
Human Site:
S365
Identified Species:
100
UniProt:
P60709
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P60709
NP_001092.1
375
41737
S365
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_850617
375
41748
S365
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
P60711
375
41718
S365
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P53478
376
41817
S366
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Frog
Xenopus laevis
O93400
375
41748
S365
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Zebra Danio
Brachydanio rerio
Q7ZVI7
375
41748
S365
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Tiger Blowfish
Takifugu rubipres
P53485
375
41748
S365
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Fruit Fly
Dros. melanogaster
P10987
376
41803
S366
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Honey Bee
Apis mellifera
XP_393368
376
41787
S366
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Nematode Worm
Caenorhab. elegans
P10984
376
41759
S366
S
K
Q
E
Y
D
E
S
G
P
S
I
V
H
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
99.7
N.A.
N.A.
100
N.A.
N.A.
98.9
99.4
98.9
98.9
97.8
97.8
97.8
N.A.
Protein Similarity:
100
N.A.
N.A.
99.7
N.A.
N.A.
100
N.A.
N.A.
99.7
100
99.7
99.7
99.7
99.7
99.4
N.A.
P-Site Identity:
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
100
100
100
100
100
100
100
N.A.
P-Site Similarity:
100
N.A.
N.A.
100
N.A.
N.A.
100
N.A.
N.A.
100
100
100
100
100
100
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
100
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
100
0
0
100
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
100
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
100
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
100
0
0
0
% I
% Lys:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
100
0
0
0
0
0
% P
% Gln:
0
0
100
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
100
% R
% Ser:
100
0
0
0
0
0
0
100
0
0
100
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
100
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
100
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _